Phenylpropanoids and polyketides
Medchemexpress LLC Ferulic acid 4-O-sulfate | 86321-29-1 | 98.1% | 274.25 | 25 MG
Ferulic acid 4-O-sulfate, also known as Ferulic acid 4-sulfate, is a significant metabolite of Ferulic acid. This compound has demonstrated a notable ability to relax arteries and reduce blood pressure in mice, indicating its potential role in cardiovascular research. Its in vitro studies show concentration-dependent relaxations in various mouse arteries, while in vivo applications have resulted in a decrease in mean arterial pressure.
- Relaxes arteries and lowers blood pressure
- Demonstrates concentration-dependent relaxations in mouse arteries
- Significantly decreases mean arterial pressure in vivo
- Intended for research and analytical applications
Apexbio Technology LLC (E,E)-Bisdemethoxycurcumin 33171-05-0 10mg
(E E)-Bisdemethoxycurcumin (CAS 33171-05-0) is a naturally derived curcuminoid and a structural analog within the demethoxycurcumin class Research demonstrates that this compound modulates multiple inflammatory signaling pathways and alters the expression of various inflammatory mediators It has been shown to induce cell cycle arrest promote apoptosis in cancer cells and inhibit proliferation-related pathways (E E)-Bisdemethoxycurcumin is widely utilized in studies investigating the molecular mechanisms of inflammation tumor cell biology and the pharmacological properties of curcuminoid derivatives
Medchemexpress LLC m-Coumaric acid (Standard) | 588-30-7 | 99.9% | 164.16 | 100 MG
m-Coumaric acid (Standard) | 588-30-7 | 99.9% | 164.16 | 100 MG
Apexbio Technology LLC 3-Carboxy-7-Hydroxycoumarin 779-27-1 250mg
3-Carboxy-7-Hydroxycoumarin (CAS 779-27-1) is a coumarin-based fluorescent molecule It is characterized by blue fluorescence emission upon excitation with ultraviolet light Structurally it features a carboxyl group that enables conjugation via carbodiimide activation (e g EDAC-mediated formation of succinimidyl ester intermediates) allowing covalent attachment to amine-containing residues in proteins and nucleic acids Based on these properties 3-Carboxy-7-Hydroxycoumarin is commonly employed in biochemical research for fluorescent labeling including analysis of protein protein interactions nucleic acid visualization and biomolecule detection assays
Medchemexpress LLC AST 487 | 630124-46-8 | 98.90% | 529.56 | 1 ML
AST 487 is a RET kinase inhibitor that inhibits RET autophosphorylation and activation of downstream effectors. It also inhibits Flt-3. This compound is suitable for laboratory research due to its diverse inhibitory activities.
- Inhibits RET (IC50=880 nM), KDR (IC50=170 nM), Flt-4 (IC50=790 nM), Flt-3 (IC50=520 nM), c-Kit (IC50=500 nM), and Abl (IC50=20 nM).
- Potently inhibits the growth of human thyroid cancer cell lines with activating mutations of RET.
- Markedly inhibits GDNF/GFRα1 and persephin-induced calcitonin mRNA at 100 nM in MTC-M cells.
- Acts as a novel, mutant FLT3 inhibitor with a Ki of 0.12 μM.
- Potently inhibits cellular proliferation (IC50<5 nM) in FLT3-ITD-Ba/F3 cells and D835Y-Ba/F3 cells.
- Results in complete cell killing of FLT3-ITD-Ba/F3 cells at 0.01 μM.
eMolecules 5472-68-4 | AstaTech | 24-DICHLORO-DL-PHENYLALANINE | 0.25g | 718055058 | 60594 | 97 | MFCD05227922 | 234.08 | C9H9Cl2NO2
AstaTech | 24-DICHLORO-DL-PHENYLALANINE | 0.25g | 718055058 | 60594 | 97.000 | 5472-68-4 | MFCD05227922 | 234.080 | C9H9Cl2NO2
Medchemexpress LLC Hesperidin methylchalcone | 24292-52-2 | 98.0% | 624.59 | 10 G
Hesperidin methylchalcone is an orally active flavonoid with analgesic, anti-inflammatory, and antioxidant properties. It exhibits vasoprotective activity and is suitable for research into gout disease.
- Orally active flavonoid
- Exhibits analgesic properties
- Acts as an anti-inflammatory agent
- Provides antioxidant benefits
- Shows vasoprotective activity
- Inhibits oxidative stress
- Reduces cytokine production
- Suppresses NF-κB activation
- Useful for gout disease research