Phenylpropanoids and polyketides
Selleck Chemical LLC Naringin S2329-500mg
Naringin (Naringoside) is a flavanone glycoside which exerts a variety of pharmacological effects such as antioxidant activity blood lipid lowering anticancer activity and inhibition of cytochrome P450 enzymes
Medchemexpress LLC Engeletin | 572-31-6 | 99.9% | 434.39 g/mol | C21H22O10 | 10 MG
Engeletin is a flavanonol glycoside reported to inhibit NF-κB signaling and to exhibit anti-inflammatory, analgesic, diuretic, and antibacterial effects. It is intended for research use only and has high solubility in DMSO but is essentially insoluble in water.
- Inhibits NF-κB signaling pathway.
- Shows anti-inflammatory and analgesic activity.
- High solubility in DMSO, insoluble in water.
- High purity (99.9%).
- Provided as a small-mass research reagent suitable for in vitro studies.
Apexbio Technology LLC Naringin 10236-47-2 10mM (in 1mL DMSO)
Naringin (CAS 10236-47-2) is a flavanone glycoside predominantly isolated from the fruit of Citrus paradisi Macfadyen (grapefruit) It is recognized for modulating various cellular pathways including inhibition of oxidative stress and inflammation through interaction with NF- B and MAPK signaling cascades Naringin has demonstrated antioxidative anti-inflammatory and potential anti-carcinogenic properties in cellular and animal models Widely used in biomedical research it serves as a tool compound for investigating mechanisms underlying chronic diseases metabolic syndromes and the modulation of drug-metabolizing enzymes For optimal stability it should be stored in a tightly sealed container under cool dry conditions
TARGETMOL CHEMICALS INC PHILLYRIN 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Phillyrin (Forsythin) is a novel AMPK activator has anti-obesity effects in nutritive obesity mice it can prevent lipid accumulation in HepG2 cells by blocking the expression of SREBP-1c and FAS through LKB1/AMPK activation. Phillyrin(Forsythin) may be a new preventive agent of acute lung injury in the clinical setting it potentially contributes to the suppression of the activation of MAPK and NF-(kappa)B pathways it also has protective effects on H2O2-induced oxidative stress and apoptosis in PC12 cells. purity: 99%
eMolecules 3,2'-Dihydroxyflavone | 6068-76-4 | MFCD00017674 | 1g
Combi-Blocks, Inc. | 3,2'-Dihydroxyflavone | 1g | 586079581 | QF-5338 | 95.000 | 6068-76-4 | MFCD00017674 | 254.241 | C15H10O4
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Medchemexpress LLC Luteolin-3-O-beta-D-glucuronide | 53527-42-7 | 25 MG
Luteolin-3-O-beta-D-glucuronide is a flavonoid compound and a metabolite of Luteolin. It is present in Rosmarinus officinalis L. and is for research use only.
- High purity: 99.02%
- Appears as a light yellow to yellow solid
- Classified as a flavonoid compound and metabolite
- Derived from Rosmarinus officinalis L.
Medchemexpress LLC Apigenin | 520-36-5 | 270.24 | 5 MG
Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor with a Ki of 2 μM. It inhibits cell proliferation in SGC-7901 cells in a dose- and time-dependent manner and possesses a broad spectrum of biological properties including antioxidative, anti-inflammatory, anticancer, and neuroprotective effects.
- Inhibits cell proliferation
- Suppresses clone formation of SGC-7901 cells
- Alleviates adriamycin-induced myocardial injury
- Reduces serum aspartate amino transferase release
- Reduces serum lactate dehydrogenase release
- Reduces serum creatine kinase contents
Apexbio Technology LLC (-)-epicatechin 490-46-0 10mM (in 1mL DMSO)
(-)-Epicatechin (CAS 490-46-0) is a flavonoid compound known for inducing pancreatic -cell regeneration and modulating nitric oxide (NO) metabolism It inhibits nitric oxide-related nitrite formation induced by interferon- and lipopolysaccharide in mouse macrophages and reduces peroxynitrite-mediated tyrosine nitration in HL-60 human leukemia cells Additionally in human endothelial cells (HUVECs) it enhances NO production displaying vasodilatory properties In diabetic rat models (alloxan-induced) (-)-epicatechin administration promotes -cell recovery reduces hyperglycemia and prevents -cell necrosis This profile underscores its research relevance for diabetes and vascular biology investigations
Sigma Aldrich Fine Chemicals Biosciences (−)-Epicatechin | 490-46-0 | MFCD00075648 | 1mg
(−)-Epicatechin | Purity: 98% | MW: 290.27 | 490-46-0 | MFCD00075648 | 1mg
TARGETMOL CHEMICALS INC 3 4 7-Trihydroxyflavone 1MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. 7,3',4'-Trihydroxyflavone inhibits osteoclastogenesis via the nuclear factor of activated T cells c1. 7,3',4'-Trihydroxyflavone can markedly inhibit the receptor activator of nuclear factor kappa B ligand-induced osteoclastic differentiation from mouse bone marrow-derived macrophages (BMMs). Purity 99.71%
Sigma Aldrich Fine Chemicals Biosciences (−)-Epicatechin | 490-46-0 | MFCD00075648 | 5mg
(−)-Epicatechin | Purity: ≥98% | Mol Wt: 290.27 | 490-46-0 | MFCD00075648 | 5mg